P2P or P-to-P may refer to:

Peer-to-peer, a type of ad-hoc computer network

Peer-to-peer file sharing, file sharing on peer-to-peer networks

Point-to-point, a telecommunications term connecting two items

Pay-to-play in gaming, politics, and music

Phenylacetone, a compound used in organic chemistry

Procure-to-pay, a sales & customer service term

People to People Student Ambassador Program, an ambassador program for students

Pin-to-pin, a technique of electrical connections for use with electronics projects where components' pins are soldered directly to each other

Partner-to-partner network, a collaboration portal

Pier to Pub, the largest open water swimming race in the world, held annually in Lorne, Australia.